The first 12 months of RECOVER has seen 116 adults and adolescents recruited to RECOVER across both UK and Irish sites. Navigating COVID restrictions, the RECOVER team successfully conducted visits across all sites utilising a mix of virtual and in-person study visits. In January 2021, the study was recognised as a clinical trial in the UK sites which led to delays in site activity for our colleagues at Belfast Health and Social Care Trust. Through hard work and determination all sites are now activated and recruitment for Phase II of RECOVER is in full swing seeing children aged 6-11 recruited since November 2021.
Our dedicated team have conducted over 400 assessments so far, many of which have already been sharedd with our International Collaborators with an aim to observe the impact Kaftrio is already having on the adult and adolescent cohort. As testament to the work by the RECOVER team, data derived from the study has already been on display at international conferences with preparation for ongoing dissemination planned for 2022.
Robyn Mulligan, a trainee clinical psychologist at Trinity College Dublin, began her research on what the experiences are of young people (12-17) who have started taking Kaftrio this year. She is exploring their expectations of the treatment compared to how they have really found it as well as the impact of this on their treatment adherence and general wellbeing. There has been an excellent response rate, and so far 17 interviews have been carried out. Inclusion of young people’s voices is an important part of the research, helping us to understand more about what works and what we can make better for patients. The results of this sub-study are expected in Summer of 2022.
Baseline data collection for the sinus and nasal disease sub-study is well underway. The questionnaire and nasal swab data we have collected so far is promising to bring much needed understanding to this under-researched area. A special thanks is deserved by our advanced imaging group in CAMI where we have been able to collect half of our baseline MRI scans in just over 2 weeks!
The achievements to date, outlined in our study milestones, could not have been met without the fantastic RECOVER participants, our PPI team, our collaborators and our research teams. For this, we would like to extend our sincere gratitude to everyone who has been involved up to this point and we look forward to continued success as we navigate through Year 2 for RECOVER and beyond.